Lifestyle

Diet and Lifestyle Program Reverses Biological Age – Neuroscience News

Summary: Diet and lifestyle programs designed to impact DNA methylation resulted in an average reduction in biological aging of 4.6 years, a new study reports.

fountain: Impact Journals

Researchers Kara N. Fitzgerald, Tish Campbell, Suzanne Makarem, and Romilly Hodges from the Institute of Medical Services, Virginia State University and the American Nutrition Association reported a series of six women who completed a methylation-supportive diet and lifestyle program. sol- DNA methylation and biological measures of aging.

“The modifiable lifestyle intervention used by participants in this case series was first investigated in a pilot clinical trial in which participants (all men between the ages of 50-72 years) reduced their biological age by an average of 3.23 years compared to controls.

“The case reported in this series led to further investigation of a modifiable lifestyle intervention, which is generally the same in other countries;” significantly in women. “

The intervention group consisted of an eight-week program. This program includes guidance on diet, sleep, exercise, and relaxation, probiotic and phytonutrient supplements, and nutritional counseling.

DNA methylation and biological age analysis (Horvath DNAmAge clock (2013), normalized using the seSAMe pipeline [a]) blood samples were taken at baseline and at the end of the eight-week period.

Five of the six participants showed a biological age reduction of between 1.22 and 11.01 years from the baseline biological age.

Statistically significant (p=.039) difference in the participants’ mean biological age before (55.83 years) and after (51.23 years) the 8-week intervention and diet and lifestyle, with an average decrease of 4.60 years.

This program includes guidance on diet, sleep, exercise, and relaxation, probiotic and phytonutrient supplements, and nutritional counseling. The image is in the public domain

The average chronological age at the beginning of the program was 57.9 years and all but one participant had a biological age younger than the chronological age at the beginning of the program, suggesting that biological changes are unrelated to age and may be attributed to disease improvement instead. underlying aging mechanisms.

“This case series of female participants extends a previous study of this intervention in men, indicating that biological age reversals can be achieved in both sexes.”

“Furthermore, the study of people with different health than those diagnosed with diseases suggests a direct link to the underlying mechanisms of aging for diseases of aging.”

News about this aging research

Author: Ryan Braithwaite
fountain: Impact Journals
Contact: Ryan Braithwaite – Impact Journals
Picture: The image is in the public domain

original research: Open access.
Potential reversal of biological age in women following an 8-week methylation-based diet and lifestyle program: a case seriesKara N. Fitzgerald et al. the aging US


Abstract

Potential reversal of biological age in women following an 8-week methylation-based diet and lifestyle program: a case series

Here we report a case series of six women who completed a methylation-supportive diet and lifestyle program to assess the impact of DNA methylation and biological measures of aging.

The intervention was an 8-week program that included controlling diet, sleep, exercise and relaxation, probiotics and phytonutrient supplements, and nutritional education.

DNA methylation and biological age analysis (Horvath DNAmAge clock (2013), normalized using the seSAMe pipeline [a]) was conducted on blood samples at baseline and at the end of the 8-week period.

Five of the six participants showed a biological age reduction of between 1.22 and 11.01 years from the baseline biological age. Statistically significant (p=.039) difference in the participants’ mean biological age before (55.83 years) and after (51.23 years) the 8-week intervention and diet and lifestyle, with an average decrease of 4.60 years.

The average chronological age at the beginning of the program was 57.9 years and all but one participant had a biological age younger than the chronological age at the beginning of the program, suggesting that biological changes are unrelated to age and may be attributed to disease improvement instead. underlying aging mechanisms.

Source link

Ava Grey

Hi there! I'm Ava Grey, an enthusiastic article writer with a passion for the arts, fashion, and staying informed about current events. As a journalism student at the New York Academy of Art, I'm driven to use my writing to create positive change and spark meaningful conversations. I'm particularly interested in contemporary art and sustainable fashion, and I love exploring how people use these mediums to express themselves and communicate their values. I believe that staying informed and hearing different perspectives is essential for personal growth and learning, and I'm always eager to engage in lively debates and discussions.

Related Articles

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button